Acap2 - ArfGAP with coiled-coil, ankyrin repeat and PH domains 2

Enables phosphatidylinositol-3,5-bisphosphate binding activity and small GTPase binding activity. Predicted to be involved in cellular response to nerve growth factor stimulus and endocytic recycling. Predicted to act upstream of or within actin filament-based process. Predicted to be located in ruffle. Predicted to be active in endosome membrane. Is expressed in several structures, including adipose tissue; brain; genitourinary system; liver; and spleen. Orthologous to human ACAP2 (ArfGAP with coiled-coil, ankyrin repeat and PH domains 2). [provided by Alliance of Genome Resources, Apr 2022]