Adgra2 - adhesion G protein-coupled receptor A2

Predicted to enable G protein-coupled receptor activity. Involved in several processes, including endothelial cell migration; positive regulation of canonical Wnt signaling pathway; and sprouting angiogenesis. Acts upstream of or within several processes, including negative regulation of vascular endothelial growth factor signaling pathway; positive regulation of endothelial cell migration; and regulation of establishment of blood-brain barrier. Located in cell surface and plasma membrane. Is expressed in several structures, including cardiovascular system; embryo mesenchyme; limb bud; mesonephros; and nose. Orthologous to human ADGRA2 (adhesion G protein-coupled receptor A2). [provided by Alliance of Genome Resources, Apr 2022]