Mtmr2 - myotubularin related protein 2

Enables identical protein binding activity and phosphatidylinositol phosphate phosphatase activity. Acts upstream of or within dephosphorylation; negative regulation of myelination; and nervous system development. Located in vacuolar membrane. Is expressed in several structures, including eye; genitourinary system; gut; immune system; and nervous system. Used to study Charcot-Marie-Tooth disease type 4B1. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 4B1. Orthologous to human MTMR2 (myotubularin related protein 2). [provided by Alliance of Genome Resources, Apr 2022]