Arid2 - AT rich interactive domain 2 (ARID, RFX-like)

Predicted to enable DNA binding activity and metal ion binding activity. Acts upstream of or within embryonic organ development; heart development; and homeostatic process. Predicted to be located in nucleoplasm and plasma membrane. Predicted to be part of transcription regulator complex. Is expressed in early conceptus and genitourinary system. Human ortholog(s) of this gene implicated in Coffin-Siris syndrome 6; colorectal cancer; and hepatocellular carcinoma. Orthologous to human ARID2 (AT-rich interaction domain 2). [provided by Alliance of Genome Resources, Apr 2022]