Ddrgk1 - DDRGK domain containing 1

Predicted to enable RNA polymerase II-specific DNA-binding transcription factor binding activity and ubiquitin-like protein ligase binding activity. Involved in several processes, including cartilage development; negative regulation of IRE1-mediated unfolded protein response; and positive regulation of protein localization to endoplasmic reticulum. Located in endoplasmic reticulum. Is expressed in central nervous system; genitourinary system; heart; and liver. Orthologous to human DDRGK1 (DDRGK domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]