Nt5c2 - 5'-nucleotidase, cytosolic II

Enables GMP 5'-nucleotidase activity. Involved in GMP catabolic process to guanine; allantoin metabolic process; and dGMP catabolic process. Located in cytosol. Is expressed in several structures, including alimentary system; integumental system; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 45. Orthologous to human NT5C2 (5'-nucleotidase, cytosolic II). [provided by Alliance of Genome Resources, Apr 2022]