Cyfip2 - cytoplasmic FMR1 interacting protein 2

Predicted to enable small GTPase binding activity. Involved in dendrite extension and positive regulation of neurotrophin TRK receptor signaling pathway. Located in synapse. Part of SCAR complex. Is expressed in several structures, including central nervous system; sensory organ; skeleton; trigeminal nerve; and urinary system. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 65. Orthologous to human CYFIP2 (cytoplasmic FMR1 interacting protein 2). [provided by Alliance of Genome Resources, Apr 2022]