Enables acyl-CoA delta5-desaturase activity. Predicted to be involved in arachidonic acid metabolic process and cellular response to starvation. Predicted to act upstream of or within long-chain fatty acid biosynthetic process and unsaturated fatty acid biosynthetic process. Predicted to be located in nucleus. Is expressed in several structures, including alimentary system; eye; genitourinary system; nervous system; and respiratory system. Orthologous to human FADS1 (fatty acid desaturase 1). [provided by Alliance of Genome Resources, Apr 2022]