Rnf139 - ring finger protein 139

Predicted to enable protease binding activity and ubiquitin protein ligase activity. Predicted to be involved in several processes, including cellular protein metabolic process; protein destabilization; and regulation of protein metabolic process. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be part of Derlin-1 retrotranslocation complex. Predicted to be active in endoplasmic reticulum. Is expressed in bladder; testis; and ureter. Human ortholog(s) of this gene implicated in renal cell carcinoma. Orthologous to human RNF139 (ring finger protein 139). [provided by Alliance of Genome Resources, Apr 2022]