Nme5 - NME/NM23 family member 5

Predicted to enable nucleoside diphosphate kinase activity. Involved in spermatid development. Acts upstream of or within several processes, including epithelial cilium movement involved in extracellular fluid movement; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway; and ventricular system development. Located in sperm flagellum. Is expressed in lung epithelium; nasal cavity respiratory epithelium; and nasopharynx epithelium. Used to study hydrocephalus. Orthologous to human NME5 (NME/NM23 family member 5). [provided by Alliance of Genome Resources, Apr 2022]