Predicted to enable thiol-dependent deubiquitinase. Acts upstream of or within positive regulation of NLRP3 inflammasome complex assembly and positive regulation of macromolecule metabolic process. Predicted to be active in several cellular components, including dendritic spine; midbody; and postsynaptic density. Predicted to be extrinsic component of endosome membrane and extrinsic component of plasma membrane. Orthologous to human USP50 (ubiquitin specific peptidase 50). [provided by Alliance of Genome Resources, Apr 2022]