Sohlh2 - spermatogenesis and oogenesis specific basic helix-loop-helix 2

Enables DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; and protein dimerization activity. Involved in oocyte differentiation; positive regulation of transcription by RNA polymerase II; and spermatogenesis. Acts upstream of or within primary ovarian follicle growth and regulation of gene expression. Predicted to be located in cytoplasm. Predicted to be active in nucleus. Is expressed in early conceptus; eye; genitourinary system; heart; and liver. Orthologous to several human genes including CCDC169-SOHLH2 (CCDC169-SOHLH2 readthrough). [provided by Alliance of Genome Resources, Apr 2022]