Crtc2 - CREB regulated transcription coactivator 2

Predicted to enable cAMP response element binding protein binding activity and chromatin binding activity. Involved in gluconeogenesis; glucose homeostasis; and positive regulation of CREB transcription factor activity. Acts upstream of or within histone H3-K9 acetylation; positive regulation of transcription by RNA polymerase II; and toxin transport. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; ear; integumental system; limb; and nervous system. Orthologous to human CRTC2 (CREB regulated transcription coactivator 2). [provided by Alliance of Genome Resources, Apr 2022]