Parn - poly(A)-specific ribonuclease (deadenylation nuclease)

Predicted to enable several functions, including cation binding activity; poly(A)-specific ribonuclease activity; and protein kinase binding activity. Acts upstream of or within nuclear-transcribed mRNA poly(A) tail shortening. Predicted to be located in nuclear speck and nucleolus. Predicted to be active in cytoplasm. Is expressed in bladder; male associated reproductive structure; testis; ureter; and urethra of male. Human ortholog(s) of this gene implicated in autosomal recessive dyskeratosis congenita 6. Orthologous to human PARN (poly(A)-specific ribonuclease). [provided by Alliance of Genome Resources, Apr 2022]