Tubb2b - tubulin, beta 2B class IIB

Predicted to enable GTP binding activity and protein heterodimerization activity. Predicted to be a structural constituent of cytoskeleton. Involved in modulation of chemical synaptic transmission. Acts upstream of or within embryonic brain development. Located in Schaffer collateral - CA1 synapse. Is expressed in several structures, including brain; large intestine; lung; sensory organ; and thymus. Used to study complex cortical dysplasia with other brain malformations 7. Human ortholog(s) of this gene implicated in complex cortical dysplasia with other brain malformations 7. Orthologous to human TUBB2B (tubulin beta 2B class IIb). [provided by Alliance of Genome Resources, Apr 2022]