Nfatc4 - nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 4

Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including brain-derived neurotrophic factor receptor signaling pathway; long-term memory; and long-term synaptic potentiation. Acts upstream of or within several processes, including circulatory system development; intracellular signal transduction; and negative regulation of cellular component organization. Located in cytosol and nucleus. Part of transcription regulator complex. Is expressed in several structures, including branchial arch; central nervous system; genitourinary system; integumental system; and sensory organ. Human ortholog(s) of this gene implicated in dilated cardiomyopathy. Orthologous to human NFATC4 (nuclear factor of activated T cells 4). [provided by Alliance of Genome Resources, Apr 2022]