Enables DNA binding activity. Acts upstream of or within cellular response to interferon-beta; defense response to virus; and positive regulation of transcription by RNA polymerase II. Located in endoplasmic reticulum and nucleus. Is expressed in hippocampus; pancreas; and testis. Orthologous to human DDX41 (DEAD-box helicase 41). [provided by Alliance of Genome Resources, Apr 2022]