Ppp2r2b - protein phosphatase 2, regulatory subunit B, beta

Predicted to enable protein phosphatase regulator activity. Predicted to be involved in several processes, including mitochondrion organization; peptidyl-serine dephosphorylation; and positive regulation of neuron apoptotic process. Predicted to act upstream of or within apoptotic process. Predicted to be located in mitochondrial outer membrane. Predicted to be part of protein phosphatase type 2A complex. Predicted to be active in cytosol. Predicted to colocalize with cytoskeleton. Is expressed in several structures, including cranial ganglion; lung; sensory organ; tongue; and viscerocranium. Human ortholog(s) of this gene implicated in Alzheimer's disease; brain disease; breast cancer; and spinocerebellar ataxia type 12. Orthologous to human PPP2R2B (protein phosphatase 2 regulatory subunit Bbeta). [provided by Alliance of Genome Resources, Apr 2022]