Tonsl - tonsoku-like, DNA repair protein

Predicted to enable histone binding activity. Predicted to be involved in double-strand break repair via homologous recombination and replication fork processing. Predicted to act upstream of or within DNA repair. Predicted to be located in nuclear body and nuclear replication fork. Predicted to be part of DNA replication factor A complex; FACT complex; and MCM complex. Is expressed in several structures, including alimentary system; brain ventricular layer; cerebellum; sensory organ; and vibrissa. Human ortholog(s) of this gene implicated in spondyloepimetaphyseal dysplasia, Sponastrime type. Orthologous to human TONSL (tonsoku like, DNA repair protein). [provided by Alliance of Genome Resources, Apr 2022]