Dusp3 - dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related)

Enables protein tyrosine/serine/threonine phosphatase activity. Involved in several processes, including cellular response to epidermal growth factor stimulus; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity; and regulation of focal adhesion assembly. Acts upstream of or within protein dephosphorylation. Predicted to be located in immunological synapse and nucleoplasm. Predicted to be active in cytosol. Is expressed in central nervous system; retina; and urinary system. Orthologous to human DUSP3 (dual specificity phosphatase 3). [provided by Alliance of Genome Resources, Apr 2022]