Involved in regulation of protein catabolic process at presynapse, modulating synaptic transmission and regulation of synaptic vesicle exocytosis. Acts upstream of or within behavioral fear response. Located in Schaffer collateral - CA1 synapse. Is active in glutamatergic synapse. Is expressed in several structures, including adrenal gland; brain; genitourinary system; gut; and respiratory system. Orthologous to human FBXL20 (F-box and leucine rich repeat protein 20). [provided by Alliance of Genome Resources, Apr 2022]