Amer2 - APC membrane recruitment 2

Predicted to enable beta-catenin binding activity and phosphatidylinositol-4,5-bisphosphate binding activity. Predicted to be involved in negative regulation of canonical Wnt signaling pathway. Predicted to act upstream of or within Wnt signaling pathway. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including adrenal gland; embryo mesenchyme; genitourinary system; nervous system; and sensory organ. Orthologous to human AMER2 (APC membrane recruitment protein 2). [provided by Alliance of Genome Resources, Apr 2022]