Trmu - tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase

Predicted to enable ATP binding activity; sulfurtransferase activity; and tRNA binding activity. Predicted to be involved in tRNA wobble position uridine thiolation. Located in mitochondrion. Used to study liver disease. Human ortholog(s) of this gene implicated in aminoglycoside-induced deafness; infantile liver failure syndrome; and transient infantile liver failure. Orthologous to human TRMU (tRNA mitochondrial 2-thiouridylase). [provided by Alliance of Genome Resources, Apr 2022]