Tmem106b - transmembrane protein 106B

Enables ATPase binding activity. Acts upstream of or within several processes, including lysosomal lumen acidification; lysosomal protein catabolic process; and positive regulation of dendrite development. Located in lysosome. Is expressed in several structures, including alimentary system; hemolymphoid system gland; integumental system; male reproductive gland or organ; and nervous system. Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy. Orthologous to human TMEM106B (transmembrane protein 106B). [provided by Alliance of Genome Resources, Apr 2022]