Rnf180 - ring finger protein 180

Enables ubiquitin conjugating enzyme binding activity and ubiquitin protein ligase activity. Acts upstream of or within several processes, including norepinephrine metabolic process; positive regulation of cellular protein metabolic process; and serotonin metabolic process. Is intrinsic component of endoplasmic reticulum membrane. Is expressed in several structures, including adrenal medulla; central nervous system; genitourinary system; lens; and thymus. Orthologous to human RNF180 (ring finger protein 180). [provided by Alliance of Genome Resources, Apr 2022]