Ankle2 - ankyrin repeat and LEM domain containing 2

Predicted to enable protein phosphatase 2A binding activity. Predicted to be involved in several processes, including mitotic nuclear membrane reassembly; negative regulation of apoptotic process; and regulation of phosphate metabolic process. Predicted to act upstream of or within cell division. Predicted to be integral component of endoplasmic reticulum membrane. Predicted to be active in endoplasmic reticulum. Human ortholog(s) of this gene implicated in primary autosomal recessive microcephaly 16. Orthologous to human ANKLE2 (ankyrin repeat and LEM domain containing 2). [provided by Alliance of Genome Resources, Apr 2022]