Cic - capicua transcriptional repressor

Enables chromatin binding activity. Involved in several processes, including learning or memory; negative regulation of transcription, DNA-templated; and social behavior. Acts upstream of or within lung alveolus development and negative regulation of transcription by RNA polymerase II. Part of protein-containing complex. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; hemolymphoid system; and sensory organ. Used to study disease of mental health. Human ortholog(s) of this gene implicated in autosomal dominant mental retardation 45. Orthologous to human CIC (capicua transcriptional repressor). [provided by Alliance of Genome Resources, Apr 2022]