Myo1e - myosin IE

Predicted to enable several functions, including actin filament binding activity; calmodulin binding activity; and microfilament motor activity. Involved in glomerular basement membrane development; glomerular filtration; and glomerular visceral epithelial cell development. Acts upstream of or within several processes, including platelet-derived growth factor receptor signaling pathway; post-embryonic hemopoiesis; and vasculogenesis. Located in adherens junction; brush border; and cytoplasm. Human ortholog(s) of this gene implicated in focal segmental glomerulosclerosis 6. Orthologous to human MYO1E (myosin IE). [provided by Alliance of Genome Resources, Apr 2022]