Ifih1 - interferon induced with helicase C domain 1

Predicted to enable several functions, including RNA binding activity; identical protein binding activity; and zinc ion binding activity. Involved in innate immune response and response to virus. Predicted to be located in mitochondrion. Predicted to be active in cytoplasm. Used to study systemic lupus erythematosus. Human ortholog(s) of this gene implicated in Aicardi-Goutieres syndrome. Orthologous to human IFIH1 (interferon induced with helicase C domain 1). [provided by Alliance of Genome Resources, Apr 2022]