Enables Lys48-specific deubiquitinase activity; thiol-dependent deubiquitinase; and ubiquitin protein ligase binding activity. Involved in several processes, including negative regulation of proteasomal protein catabolic process; protein K48-linked deubiquitination; and protein stabilization. Located in cytosol. Is expressed in ovary and primary sex cord. Orthologous to human USP19 (ubiquitin specific peptidase 19). [provided by Alliance of Genome Resources, Apr 2022]