Septin12 - septin 12

Predicted to enable several functions, including GTP binding activity; GTPase activity; and protein homodimerization activity. Involved in flagellated sperm motility. Predicted to be located in several cellular components, including midbody; perinuclear region of cytoplasm; and sperm annulus. Predicted to be part of septin complex. Predicted to be active in cell division site; microtubule cytoskeleton; and septin ring. Human ortholog(s) of this gene implicated in spermatogenic failure 10. Orthologous to human SEPTIN12 (septin 12). [provided by Alliance of Genome Resources, Apr 2022]