Spef1 - sperm flagellar 1

Enables microtubule binding activity. Involved in axonemal central apparatus assembly; cilium movement; and negative regulation of microtubule depolymerization. Located in 9+2 motile cilium; axonemal central apparatus; and ciliary tip. Is expressed in several structures, including central nervous system; gut; reproductive system; respiratory system; and sensory organ. Orthologous to human SPEF1 (sperm flagellar 1). [provided by Alliance of Genome Resources, Apr 2022]