Nos1ap - nitric oxide synthase 1 (neuronal) adaptor protein

Enables nitric-oxide synthase binding activity. Predicted to be involved in several processes, including positive regulation of peptidyl-cysteine S-nitrosylation; postsynaptic actin cytoskeleton organization; and regulation of ion transmembrane transport. Located in Z disc; mitochondrion; and sarcoplasmic reticulum membrane. Colocalizes with T-tubule and caveola. Is expressed in several structures, including brain; gallbladder; spinal cord; trachea; and urinary system. Human ortholog(s) of this gene implicated in nephrotic syndrome type 22. Orthologous to human NOS1AP (nitric oxide synthase 1 adaptor protein). [provided by Alliance of Genome Resources, Apr 2022]