Inf2 - inverted formin, FH2 and WH2 domain containing

Predicted to enable actin binding activity and small GTPase binding activity. Acts upstream of or within regulation of cellular component size. Predicted to be located in perinuclear region of cytoplasm. Is expressed in several structures, including adipose tissue; alimentary system; hemolymphoid system; nervous system; and reproductive system. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease dominant intermediate E and focal segmental glomerulosclerosis 5. Orthologous to human INF2 (inverted formin 2). [provided by Alliance of Genome Resources, Apr 2022]