Megf10 - multiple EGF-like-domains 10

Enables Notch binding activity. Involved in several processes, including myoblast migration; skeletal muscle satellite cell differentiation; and skeletal muscle satellite cell proliferation. Acts upstream of or within apoptotic process involved in development; engulfment of apoptotic cell; and recognition of apoptotic cell. Located in phagocytic cup. Is expressed in several structures, including cerebellum; dorsal root ganglion; retina layer; skeletal muscle tissue; and testis. Human ortholog(s) of this gene implicated in early-onset myopathy-areflexia-respiratory distress-dysphagia syndrome. Orthologous to human MEGF10 (multiple EGF like domains 10). [provided by Alliance of Genome Resources, Apr 2022]