Enables iodotyrosine deiodinase activity. Predicted to be involved in thyroid hormone metabolic process and tyrosine metabolic process. Predicted to be located in cytoplasmic vesicle membrane; nucleoplasm; and plasma membrane. Predicted to be integral component of plasma membrane. Is expressed in thyroid gland. Human ortholog(s) of this gene implicated in thyroid dyshormonogenesis 4. Orthologous to human IYD (iodotyrosine deiodinase). [provided by Alliance of Genome Resources, Apr 2022]