Fuz - fuzzy planar cell polarity protein

Involved in several processes, including embryonic morphogenesis; non-motile cilium assembly; and regulation of signal transduction. Acts upstream of or within several processes, including animal organ development; embryonic digit morphogenesis; and positive regulation of protein processing. Predicted to be located in cell projection; cytoplasm; and cytoskeleton. Is expressed in several structures, including central nervous system; neural ectoderm; and notochord. Human ortholog(s) of this gene implicated in neural tube defect. Orthologous to human FUZ (fuzzy planar cell polarity protein). [provided by Alliance of Genome Resources, Apr 2022]