Cyp2c66 - cytochrome P450, family 2, subfamily c, polypeptide 66

Predicted to enable several functions, including caffeine oxidase activity; heme binding activity; and monooxygenase activity. Acts upstream of or within hematopoietic progenitor cell differentiation. Predicted to be active in cytoplasm and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in several diseases, including Plasmodium falciparum malaria; end stage renal disease; eosinophilic esophagitis; invasive aspergillosis; and multiple chemical sensitivity. Orthologous to several human genes including CYP2C19 (cytochrome P450 family 2 subfamily C member 19). [provided by Alliance of Genome Resources, Apr 2022]