Bst2 - bone marrow stromal cell antigen 2

Predicted to enable metalloendopeptidase inhibitor activity and protein homodimerization activity. Involved in several processes, including negative regulation of intracellular transport of viral material; negative regulation of viral genome replication; and response to interferon-gamma. Located in cell surface. Is expressed in retina. Human ortholog(s) of this gene implicated in acquired immunodeficiency syndrome and endometrial cancer. Orthologous to human BST2 (bone marrow stromal cell antigen 2). [provided by Alliance of Genome Resources, Apr 2022]