Enables protein kinase activator activity. Acts upstream of or within positive regulation of MAPK cascade. Predicted to be active in nucleus. Is expressed in several structures, including adrenal gland; central nervous system; heart; pancreas; and retina. Human ortholog(s) of this gene implicated in syndactyly-telecanthus-anogenital and renal malformations syndrome. Orthologous to several human genes including CCNQ (cyclin Q). [provided by Alliance of Genome Resources, Apr 2022]