Predicted to enable ubiquitin-protein transferase activity. Predicted to be involved in several processes, including intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; proteasome-mediated ubiquitin-dependent protein catabolic process; and protein ubiquitination. Predicted to be integral component of membrane. Predicted to be active in endoplasmic reticulum membrane. Orthologous to human RNF186 (ring finger protein 186). [provided by Alliance of Genome Resources, Apr 2022]