Prdm5 - PR/SET domain 5

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; DNA-binding transcription factor binding activity; and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in histone modification; mitotic cell cycle; and negative regulation of transcription by RNA polymerase II. Predicted to act upstream of or within cellular response to leukemia inhibitory factor. Predicted to be located in nuclear body and nucleolus. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in brittle cornea syndrome 2. Orthologous to human PRDM5 (PR/SET domain 5). [provided by Alliance of Genome Resources, Apr 2022]