Predicted to enable calcium ion binding activity. Predicted to be involved in several processes, including negative regulation of Rho protein signal transduction; negative regulation of Rho-dependent protein serine/threonine kinase activity; and negative regulation of membrane permeability. Predicted to act upstream of or within several processes, including circulatory system development; endothelial cell morphogenesis; and lymph circulation. Predicted to be located in cell-cell junction and external side of plasma membrane. Orthologous to human HEG1 (heart development protein with EGF like domains 1). [provided by Alliance of Genome Resources, Apr 2022]