Zfand2b - zinc finger, AN1 type domain 2B

Enables K48-linked polyubiquitin modification-dependent protein binding activity and ubiquitin binding activity. Involved in proteasome-mediated ubiquitin-dependent protein catabolic process; protein targeting to ER; and regulation of insulin-like growth factor receptor signaling pathway. Located in endoplasmic reticulum. Is anchored component of membrane. Part of proteasome complex. Orthologous to human ZFAND2B (zinc finger AN1-type containing 2B). [provided by Alliance of Genome Resources, Apr 2022]