Enables transcription coactivator activity and transcription corepressor activity. Acts upstream of or within chromatin remodeling and nervous system development. Located in nucleus. Part of histone deacetylase complex. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; neural retina; and vibrissa. Orthologous to human RERE (arginine-glutamic acid dipeptide repeats). [provided by Alliance of Genome Resources, Apr 2022]