Predicted to enable ubiquitin conjugating enzyme binding activity and ubiquitin protein ligase activity. Predicted to act upstream of or within several processes, including norepinephrine metabolic process; positive regulation of cellular protein metabolic process; and serotonin metabolic process. Predicted to be intrinsic component of endoplasmic reticulum membrane. Orthologous to human RNF180 (ring finger protein 180). [provided by Alliance of Genome Resources, Apr 2022]