Atr - ATR serine/threonine kinase

Predicted to enable MutLalpha complex binding activity; MutSalpha complex binding activity; and protein serine/threonine kinase activity. Involved in response to arsenic-containing substance and response to xenobiotic stimulus. Predicted to be located in Golgi apparatus; PML body; and XY body. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in Seckel syndrome 1; adenoid cystic carcinoma; colon cancer; lung cancer; and pancreatic cancer. Orthologous to human ATR (ATR serine/threonine kinase). [provided by Alliance of Genome Resources, Apr 2022]