H4f3 - H1.3 linker histone, cluster member

Predicted to enable double-stranded DNA binding activity and nucleosomal DNA binding activity. Predicted to be involved in chromosome condensation; negative regulation of DNA recombination; and nucleosome positioning. Predicted to act upstream of or within histone H3-K27 trimethylation; histone H3-K4 trimethylation; and negative regulation of transcription by RNA polymerase II. Predicted to be located in euchromatin. Predicted to be part of nucleosome. Predicted to be active in nucleus. Orthologous to human H1-3 (H1.3 linker histone, cluster member). [provided by Alliance of Genome Resources, Apr 2022]