Snx3 - sorting nexin 3

Predicted to enable phosphatidylinositol phosphate binding activity; protein phosphatase binding activity; and retromer complex binding activity. Predicted to be involved in several processes, including endosomal transport; intralumenal vesicle formation; and negative regulation of transport. Predicted to act upstream of or within several processes, including hemoglobin biosynthetic process; regulation of intracellular protein transport; and transferrin transport. Predicted to be located in cytoplasmic vesicle and cytosol. Predicted to be part of retromer complex. Predicted to be active in early endosome membrane. Human ortholog(s) of this gene implicated in syndromic microphthalmia 8. Orthologous to human SNX3 (sorting nexin 3). [provided by Alliance of Genome Resources, Apr 2022]