Ndufs3 - NADH:ubiquinone oxidoreductase core subunit S3

Enables NADH dehydrogenase (ubiquinone) activity. Involved in mitochondrial electron transport, NADH to ubiquinone and mitochondrial respiratory chain complex I assembly. Located in mitochondrion. Part of mitochondrial respiratory chain complex I. Is expressed in several structures, including alimentary system; ear; genitourinary system; integumental system; and nervous system. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 8. Orthologous to human NDUFS3 (NADH:ubiquinone oxidoreductase core subunit S3). [provided by Alliance of Genome Resources, Apr 2022]